Answer 3 for NUR 550 Consider ecological and global issues, social determinants of health, principles of genetics, and genomics

Translational research, which aims to use the findings of basic and clinical research to arrive at practical conclusions, may be beneficial in many areas that reflect the load of disease on a global scale. These areas include ecological and global social determinants of health, genetics, and genomics, as proposed by Clayton et al. (2023). This approach provides a suitable and swift method through which the advancements in science are incorporated into workable solutions benefiting the globe’s health.

The concept of translational research regarding ecological and global problems in focus can potentially help in developing the best approaches to the management of the effects of climate change. For example, the information from scientific production regarding warmth-tolerant plant species can be incorporated into farming systems that nourish communities threatened by rising temperatures (Janni et al., 2024). Similarly, knowledge of vector-borne diseases can demonstrate ways to implement improved preventive strategies for areas that undergo an ecosystem shift due to global warming.

Concerning social determinants of health, translational interventions hope to solve the health disparity problem by developing interventions that will enhance the proper health and socioeconomic factors among human beings. For instance, enlightened empirical research on the impacts of education on health helps develop and implement arrangements that may improve health knowledge and healthcare organizations for societies permanently excluded from mainstream health structures (Doubeni et al., 2022). Besides, through the translated intervention, more details may help develop policies desiring to solve disparities in delivering healthcare.

Moreover, translational research has critical significance in the genetic and genomic area, including in the creation of personalized medicine. Molecular genetic work on diseases and disease risk factors entails the possibility of use in screening and prevention strategies (Buchanan et al., 2020). In addition, exploring gene therapies leads to more breakthroughs in eradicating previously incurable hereditary diseases and significantly reducing world disease incidence.

References

Buchanan, A. H., Lester Kirchner, H., Schwartz, M. L. B., Kelly, M. A., Schmidlen, T., Jones, L. K., Hallquist, M. L. G., Rocha, H., Betts, M., Schwiter, R., Butry, L., Lazzeri, A. L., Frisbie, L. R., Rahm, A. K., Hao, J., Willard, H. F., Martin, C. L., Ledbetter, D. H., Williams, M. S., & Sturm, A. C. (2020). Clinical outcomes of a genomic screening program for actionable genetic conditions. Genetics in Medicine: Official Journal of the American College of Medical Genetics22(11), 1874–1882. https://doi.org/10.1038/s41436-020-0876-4

Clayton, E. W., Smith, M. E., Anderson, K. C., Chung, W. K., Connolly, J. J., Fullerton, S. M., McGowan, M. L., Peterson, J. F., Prows, C. A., Sabatello, M., & Holm, I. A. (2023). Studying the impact of translational genomic research: Lessons from eMERGE. The American Journal of Human Genetics110(7), 1021–1033. https://doi.org/10.1016/j.ajhg.2023.05.011

Doubeni, C. A., Nelson, D., Cohn, E. G., Paskett, E., Asfaw, S. A., Sumar, M., Ahmed, S. M., McClinton-Brown, R., Wieland, M. L., Kinney, A., Aguilar-Gaxiola, S., Rosas, L. G., & Patino, C. M. (2022). Community engagement education in academic health centers, colleges, and universities. Journal of Clinical and Translational Science6(1), e109. https://doi.org/10.1017/cts.2022.424


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